ALIUD PHARMA GmbH & Co. KG located in Laichingen, Germany, is a global bio-pharmaceutical company. ALIUD Pharma is a 100% subsidiary of STADA Arzneimittel AG. The company was founded in 1986 by Egon F. Siebein.
MECHANISM OF ACTION
Piracetam’s mechanism of action is not fully understood. It is a cyclic derivative of GABA, yet GABA receptors and metabolism appear to not be affected. It is neither, a sedative or a stimulant but is known to influence cognitive ability. Piracetam is also believed to be a vasodilator and a circulatory agent but this is not believed to be its main nootropic action.
PIRACETAM USES (MEDICAL)
Piracetam is used in some countries as a medical agent and is administered for a wide range of purposes. Its primary medical use is as a neuro-protective agent before or after stroke. The substance is believed to reduce the risk of ischemic stroke as well as minimize post-stroke damages to the brain. It is also an anti-coagulant and anti-thrombotic agent which is often used safety in conjunction with other therapies.
Piracetam has proven to be safe, with low toxicity, side effects and drug interactions. Evidence shows it may have validity in treating symptoms of dyslexia and a host of learning disabilities and neurological disorders but this should not be relied on as therapy without consultation of a licensed medical practitioner.
Piracetam has been used for decades as an off label nootropic agent. It has been observed to be effective in increasing: cognition and memory, learning, focus and reaction times but these results seem to vary. Below are some of the benefits that have been reported off label and in medical studies.
Piracetam is believed to reduce free radicals in the brain that caused oxidative stress. Oxidative stress can be a cause of cholinergic damages that can lead to Alzheimer’s and Dementia as well as other neurological disorders.
PIRACETAM SAFETY, TOLERANCE & DRUG INTERACTIONS
Some people may experience allergic reactions as a result of taking Piracetam. Individuals who are prone to experiencing medication reactions in general may be at a higher risk than others, and they should consult with their physicians. However, other than this high-risk group, people usually won’t experience any major side effects as a result of taking Piracetam, even at higher doses. Some of the patients taking it might experience mild headaches, gastrointestinal symptoms, and sleeping problems. However, overall, Piracetam is a safe nootropic for all but the most high-risk populations to take.
Piracetam goes well in combination with other nootropics. It goes especially well with a choline source and this is always recommended.
The usual dose is 2,400 to 4,800 mg per day in three divided doses. Some literature recommends a high "attack" dose (approximately 4,000 to 8,000 mg) be taken for the first two days. Piracetam takes effect within 30 to 60 minutes.